Scientific principles for the identification of endocrine-disrupting chemicals: A consensus statement.
Solecki, R., et.al., Archives of Toxicology, (2016), V.91(2), p. 1001–1006.
This paper provides summary information about a consensus reached by a group of twenty-three international world-leading scientists from different disciplines at an expert meeting hosted by the German Federal Institute for Risk Assessment (BfR) in Berlin that can serve as the basis for the development of ED criteria in relevant EU legislation. The paper discusses the consensus reached on background, definition of an ED and related concepts, sources of uncertainty, scientific principles important for ED identification, and research needs. It highlights the difficulty in retrospectively reconstructing ED exposure, insufficient range of validated test systems for EDs, and some issues impacting on the evaluation of the risk from EDs.